Journalists caught a glimpse of it during the Medal of Honor ceremony — a red, irritated patch on the right side of President Donald Trump's neck. Soon, dermatologists across the country were weighing in on the possible cause, and social media was flooded with speculation. Dr. Sean Barbabella, President Trump's physician and Director of the White House Medical Unit, stated it was from a "preventative skin treatment." But for the 58 million Americans already living with Actini

Cover Image: BRITISH NUTRITION FOUNDATION. Fibre - Nutrition Information - British Nutrition Foundation [Internet]. British Nutrition Foundation. 2023. Available from: https://www.nutrition.org.uk/nutritional-information/fibre/ What is Fiber? ‌Dietary fiber is a type of plant-based carbohydrate that the human body cannot digest or absorb. Fiber is an important component of a healthy diet. It helps prevent constipation, lower cholesterol, manage blood sugar and reduce the risk

Image was designed by the Author Introduction Colorectal cancer (CRC) is a malignancy that originates in the colon or rectum, both of which are part of the large intestine. Millions of people globally are diagnosed with this disease, leading to approximately one million deaths each year. While CRC traditionally affected older individuals, it is now increasingly being diagnosed in people under the age of 50, with men being more affected than women [1]. In the absence of effect

Colorectal cancer is one of the most common cancers worldwide. Despite its prevalence, it is also one of the most preventable and treatable forms of cancer when detected early. It affects the colon and rectum, key parts of the digestive system, and often develops silently (1). That’s why awareness about its risks, symptoms, and screening options isn’t just important, it can be lifesaving. What Is Colorectal Cancer? Colorectal cancer develops when abnormal cells grow unc

Lyn Lumia Why do people with cancer use Alternative Medicine? People with cancer might think about using Alternative Medicine for a number of reasons: They want to do everything they can to fight the cancer. They are seeking a treatment approach that might have fewer side effects. They want to be able to control how their cancer is treated. They prefer alternative theories of health and disease, as well as alternative treatments. They may have seen information online or in ot

Figure 1: Utilization of the RADO Approach (AI Generated) When your child receives a cancer diagnosis it’s normal to feel helpless watching them struggle with anxiety, fear, and uncertainty, especially when it affects their quality of life. Children with cancer often experience significant anxiety regarding procedures, chemotherapy, pain, appearance changes, and the future. This stress can trigger sleep problems, headaches, stomachaches, and other physical symptoms that inten

Author Micah Sagini * For a long time, cervical cancer has been a global health concern for women globally. Cervical cancer ranks fourth among cancer-related causes of death in women worldwide, with more than 500,000 new cases and around 300,000 deaths each year. Unlike most cancers, cervical cancer is caused by a virus known as human papillomavirus (HPV), which infects the human reproductive system. This virus is responsible for over 95% of cervical cancer cases [1]. The d

Image obtained from https://angio.org/about-angiogenesis/ Think of a tumor as a fast-growing city. To sustain a rising population, it needs new roads to bring in essential supplies. These roads take the form of blood vessels, transporting oxygen and nutrients to feed the growing tumor. Tumors have the ability to construct these roads or vessels at a very fast rate, but what if we could halt construction by cutting off supply from the outside? Instead of attacking the city

Introduction Precision medicine is often associated with cancer care. Advances in tumor sequencing, targeted therapies, and biomarker-guided clinical trials have positioned oncology as the flagship application of this approach, shaping public perception to equate precision medicine exclusively with cancer treatment. However, what if these advancements extend beyond oncology? At its core, precision medicine is about understanding variability in genetics, environment, and lifes

Introduction Non-Small Cell Lung Cancer (NSCLC) harboring mutations in the Human Epidermal Growth Factor Receptor 2 (ERBB2 or HER2) represents a distinct and historically challenging clinical subset, accounting for approximately 2–4% of all NSCLC cases. While the therapeutic landscape has recently evolved with the approval of antibody-drug conjugates (ADCs) like trastuzumab deruxtecan (T-DXd), an effective, brain-penetrant, and tolerable oral tyrosine kinase inhibitor (TKI) h

Natural Killer cells are part of the body’s innate immune system. Think of them as fast-acting armed guards—they’re the body’s first responders to threat. Scientists are working on turning these cells into something more akin to trained assassins. Numerous and diverse studies are being conducted around the world to use them against cancer. (1, 11) NK cells got their name in 1975 when Swedish researchers discovered them in mice. What made them unique was their ability to quick

The American Cancer Society has shared encouraging news: 70% of people in the U.S. now live at least five years after a cancer diagnosis. For many older adults, this milestone offers real hope and reassurance. Back in the 1970s, only half of patients reached the five‑year mark. Even in the 1990s, the number was closer to 63%. Today’s progress reflects decades of better treatments, earlier detection, and healthier habits. Why This Matters for Older Adults Many seniors worry t

Author Micah Sagini CXCR4 is a chemokine receptor that is associated with the development of cancer and other inflammatory disorders. The endogenous inhibitor of CXCR4 known as EPI-X4, is a recently discovered peptide from human serum albumin that inhibits C-X-C chemokine receptor type 4 (CXCR4). Chemokines are small signaling proteins (8–12 kDa) that interact with G-protein-coupled receptors to regulate physiological processes in the body. One of the most studied chemokines

Our immune system wields immense power, but things don’t always go to plan. Sometimes it tries to help and succeeds. Other times, it fails and makes things worse. Gamma delta T-Cells are extremely effective at detecting and killing cancer cells. But certain subsets release IL-17, and depending on the type of cancer, that can make things worse.

CAR-T Therapy as a Foundational Treatment for Cancer Chimeric antigen receptor T-cell therapy has become a cornerstone in the treatment of malignancies, as it offers a specialized and targeted approach to killing cancerous cells. Despite its evidenced success, the use of CAR-T cell therapy as a standalone treatments comes with many challenges and drawbacks. For example, patients can experience resistance to treatments or disease relapse. Furthermore, minimal residual disease

Introduciton Triple-negative breast cancer (TNBC) represents the subtype of breast cancer with the least favorable outcomes, largely due to its aggressive molecular features and a historic lack of effective targeted treatment options. However, the landscape of oncology is shifting with the rise of Antibody-Drug Conjugates (ADCs). Based on the concept of the "magic bullet" first proposed by Paul Ehrlich, ADCs are designed to selectively deliver cytotoxic chemotherapy directly

Breast cancer is the leading cause of cancer deaths in women globally. According to the WHO report of 2022, there were 0.67 million deaths and 2.3 million cases of breast cancer worldwide. These alarming figures call for a concerted effort by various stakeholders and organizations to address this issue. Early screening through mammography is the fundamental and recommended approach for identifying women at risk of developing breast cancer [1]. High breast density, also known

Introduction Small-cell lung cancer (SCLC) is one of the most aggressive and difficult-to-treat forms of cancer, characterized by rapid growth and early metastasis. For decades, patients who progressed after initial platinum-based chemotherapy faced poor prognoses and limited treatment options, often relying on older chemotherapy agents with modest efficacy and high toxicity. This landscape shifted significantly on November 19, 2025, when the U.S. Food and Drug Administration

Introduction Imagine a cancer treatment designed entirely for you, built using the exact mutations inside your tumor, and created with the goal of training your immune system to eliminate every trace of cancer cells that remain after surgery or therapy. This idea once sounded like science fiction. Today, it’s becoming reality.Ultra-personalized cancer vaccines are emerging as one of the most exciting developments in precision medicine, offering a new way to harness our immune

Introduction DICER1 is a gene that plays a crucial role in microRNA (miRNA) processing and, by extension, the regulation of gene expression. Germline mutations in DICER1 cause DICER1 syndrome, a rare autosomal dominant hereditary cancer predisposition syndrome primarily affecting children and young adults. Recognizing the clinical spectrum of DICER1-related disorders is essential for early detection, surveillance, and genetic counseling. What is the DICER1 Gene? The DICER1 g