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Regional Epidemiology of Sickle Cell Disease Patients: Identifying Trends, Hotspots, and Data Deficiencies
Graphic illustration depicting sickle cell disease, retrieved from: https://my.clevelandclinic.org/health/diseases/4579-sickle-cell-anemia In the United States alone, 100,000 individuals suffer from sickle cell anemia, more commonly known as sickle cell disease. Out of this population, around 90,000 are of African American Descent; it is hypothesized that the gene mutation responsible (HBB) was acquired due ot the environmental defense mechanism of fighting against malaria, m
Denby Williams
Feb 54 min read


How Is Iron Deficiency Linked to Being Tired?
Introduction We all live in hectic times and its natural to feel tired after a long day's work. But if youre feeling tired all the time - like after a good night's sleep or minimal work, then maybe there's an underlying condition that people often overlook - iron deficiency. People brush off fatigue as stress or blame it on a bad sleep the previous night. But the cause is probably hidden deeper in your blood. Iron deficiency is a very common issue all over the world; and fati
nakshatrah2
Jan 192 min read


Hemochromatosis: common yet little known genetic disorder
Introduction Many of us have occasionally felt very tired and achy, and perhaps thought that it could be due to iron deficiency. However, not many people would think that the symptoms they are experiencing could actually be caused by too much iron in their body. Over time, excess iron can build up in organs such as the liver, heart, and pancreas, which may lead to long-term complications, if left untreated. 1–3 What is hemochromatosis? Hemochromatosis is a condition in which
Aleksandra Erac-Zganec
Jan 194 min read


Bruises: what are they and why do they change colour?
I broke my toe recently and found myself with a huge bluish green bruise occupying the whole side of my leg. It was interesting to watch the myriad of colours that followed before the bruise disappeared. But it got me thinking - what causes this colour carousel and why does it happen exactly? What Exactly Is a Bruise? A bruise or ecchymosis happens when tiny blood vessels under the skin because of an impact or injury, aging skin and certain medications. The blood leaks into t
nakshatrah2
Jan 183 min read


Sickle Cell Disease, & it's Epidemiology in the United States
A scanning electron microscope of blood cells, By: National Cancer Institute (NCI) Introduction "Sickle cell disease (SCD) is a group of inherited red blood cell disorders." (Centers for Disease Control and Prevention [CDC], 2025, Overview section, para. 1). Red blood cells contain hemoglobin, and hemoglobin is a protein that carries oxygen. (CDC, 2025, Overview section, para. 1). In a person with sickle cell disease, the hemoglobin is abnormal which leads to red blood cells
Sina Amadi
Jan 113 min read


What Is PRP? How Platelet-Rich Plasma Works and When It Might Help You
What Platelet-Rich Plasma and How is it Made? Platelet-rich plasma, or PRP, is a treatment that uses a person’s own blood to stimulate healing in tissues. Blood is made up of several parts, among them being platelets and plasma. Platelets are best known for their clotting ability, but they can also carry growth factors that support tissue repair. Plasma is the liquid portion of the blood. To perform a PRP injection, a provider will draw a vial of the patient’s blood and spi
myleebrown2021
Dec 27, 20253 min read


What is Thalassemia? A Comprehensive Overview
Thalassemia – a type of anemia Anemia is defined as a decrease in Red Blood Cells (RBCs) counts below normal. Any significant decrease in RBCs, its essential components—hemoglobin or hematocrit—or any combination of these values fall under anemia. The reason for decreased hemoglobin or hematocrit does not matter, whether through iron deficiency, lead poisoning, thalassemia, kidney failure, cancer, or even something as straightforward as blood loss. As a result, common sympt
Andrew Look
Nov 18, 202510 min read


Understanding Blood Cancers: A Comprehensive Overview
Pictured edited from canva Blood cancers are a group of malignancies that begin in the blood, bone marrow, or lymphatic system. Unlike solid tumors, these cancers disrupt the production and function of normal blood cells, weakening the body’s ability to fight infection, transport oxygen, and regulate vital immune responses. Types of Blood Cancer The three main categories are: Leukemia : Cancer of the blood and bone marrow, characterized by the uncontrolled growth of abnorma
Kafayat Yusuf
Nov 15, 20253 min read


Lab-Grown Blood: The Future of Transfusions
In today’s fast-moving world of medicine, it’s no surprise that laboratories are beginning to reshape the way we think about blood transfusions. One of the most exciting steps in this direction is the RESTORE study —a clinical trial that, for the first time, transfused red blood cells grown entirely in a lab into human volunteers. Unlike traditional transfusions, this experiment used cells generated from adult stem cells, creating a small but history-making “mini-transfusion.
Saniya Jassal
Nov 15, 20252 min read


Atherosclerosis- The Silent Killer
Figure 1. Comparison of a healthy artery compared to one with a plaque formation (atherosclerosis), causing a narrowed artery for blood...
aaz206
Sep 6, 20254 min read


Cold Intolerance and Underlying Health Conditions: An Overview
Did you know that cold intolerance might be your body’s way of signaling an underlying health condition? While most people know the...
Nivetha B Manohar
Jul 29, 20253 min read


Should I be worried about hypoglycaemia?
Hypoglycaemia is defined as a condition where a person’s blood glucose levels are below the standard range. Clinically, hypoglycaemia is...
Takudzwa
Jul 18, 20253 min read


Why All That Blood Work Before a Kidney Transplant Actually Matters
Over 90,000 people are waiting for a kidney transplant in the United States. People who need a transplant start with an evaluation. The...
Anne Denk
Jul 7, 20253 min read


Blood and its roles in homeostasis, infection, and cancer
Blood is a specialized fluid connective tissue that supports and connects all body systems [1, 2, 8, 11, 13]. Its three main functions...
Myr Selvage
Jun 29, 20259 min read


Myelofibrosis: Bringing Hope with New Treatments
Myelofibrosis (MF) is a rare blood cancer that causes scarred bone marrow tissue. Excessive scar tissue makes it difficult for MF...
Michelle Karth
Jun 23, 20255 min read


Sickle Cell Disease in India: Challenges, Advances, and the Path to Elimination
scientificanimations.com Sickle cell disease (SCD) is an inherited group of blood disorders characterized by the abnormal hemoglobin...
Rachelle DiMedia
Jun 19, 20256 min read


Understanding Hemoglobin A1C and How to Keep it Low
Hemoglobin A1C is a blood test used to diagnose and monitor prediabetes and diabetes type 2. Understanding the results of routine blood...
Mali Arwyn
May 21, 20254 min read


Understanding Hemophilia
Image of a stethoscope that is laying on top of a beige colored countertop. By: CDC/Debora Cartagena Introduction Hemophilia is typically...
Sina Amadi
May 15, 20252 min read


Do the SIRS Criteria Still Hold Value in Sepsis Identification and Intervention?
Introduction Sepsis is a life-threatening condition characterized by the body's dysregulated response to infection, leading to organ...
Jennifer John
May 2, 20253 min read


The Impact of Changing Automated Blood Pressure Measurement Devices on Pediatric Blood Pressure
Elevated high blood pressures used to be common in adults, but recent data across the United States and Canada have shown they’re also a...
Deborah Sabinus-Chinonso
May 1, 20255 min read
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