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Oral GLP-1 Receptor Agonist in Diabetes Management
Photo Credit : Wix Diabetes is the ranked the seventh leading cause of death in the United States and a major contributor to cardiovascular disease, the leading cause of death in the United States. According to the latest Center for Disease Control (CDC) report, 40.1 million people in the United States had diabetes in 2023, with a 90%-95% having Type 2 diabetes mellitus (T2DM). What is T2DM? T2DM is a chronic metabolic disorder characterized by hyperglycemia, insulin resistan
Deepti Kumar
1 day ago3 min read


Painkillers - Which one should you choose and when
Painkillers are some of the most commonly available over-the-counter drugs in the world. Whether it's for muscle cramp, a twisted ankle, an aching tooth or a nasty fall that required stitches, pain killers are literal life savers for many, if not all of us. When there are so many options to choose from, which one do you go with? While every single ache or cramp isn't probably a visit-the-doctor situation, it's still necessary to be informed about the type of painkiller you ne
nakshatrah2
6 days ago4 min read


Roxadustat: A New Oral Treatment for Anemia in Kidney Disease
A New Pill That Helps Treat Anemia in Kidney Disease Many patients who have chronic kidney disease will develop anemia, which means their blood does not carry enough oxygen throughout the body. This can cause people feel very tired, weak, dizzy, and short of breath. Many current treatments require shots and frequent visits to a clinic, which can be stressful and inconvenient. A new pill taken by mouth called roxadustat is offering a simpler option. Roxadustat helps the body m
Ariel Berger
May 12 min read
Feel Like Yourself Again with Bioidentical Hormone Pellet Therapy
Feel Like Yourself Again with Bioidentical Hormone Pellet Therapy Linda Boone BSN, RN Bioidentical hormones are plant-derived compounds, typically sourced from soy or yams, that are structurally identical to the hormones naturally produced by the body. Estradiol and testosterone pellets are made to mirror the body’s natural molecular hormone structure. Common types of bioidentical hormone replacement prescriptions include gels, patches, pills, creams, and vaginal inserts. Som
Linda Boone
Apr 293 min read


Dordaviprone: A First-in-Class ClpP Activator for H3 K27M-Mutant Gliomas
Introduction Diffuse midline gliomas (DMGs) harboring the H3 K27M mutation (now classified as H3 K27M-altered diffuse midline glioma) represent one of the most devastating diagnoses in neuro-oncology. These tumors, which arise in critical midline structures like the thalamus and brainstem (e.g., DIPG), predominantly affect children and young adults. Historically, they have been uniformly fatal, with radiation therapy offering only transient palliative benefit and chemotherapy
Fay
Apr 123 min read


Why You Should Always Complete Your Antibiotics Course
Antibiotics are widely used to treat bacterial infections (not viral!). They are wonder drugs that are basically a bacteria's kryptonite. But many people stop taking antibiotics as soon as they start feeling better. When the fever goes goes down, the throat feels better and the pain lets off, it might feel like the worst of the infection has passed. This might tempt many from completing the full prescribed course. While it may seem harmless (after all its only a pill or two r
nakshatrah2
Apr 92 min read


Semaglutide: What you need to know
Image credit: Freepik According to the World Health Organization, obesity is a chronic disease resulting from complex interactions of genetics, neurobiology, and environment. In the U.S. adult obesity rates have doubled in the past three decades from 19% in 1990 to more than 42% in 2022. Moreover, a new study estimates 47% of adults in the U.S. to be affected by obesity by 2035. Consequently, a search for a safe and effective treatment has been an ongoing pursuit. Semaglutide
Priya Kumar
Mar 282 min read


Common Medication Mistakes Patients Make and How to Avoid Them
You feel better after a few days of treatment and decide to stop the medicine. You cannot remember whether you already took today’s dose. You take an over-the-counter tablet along with your prescription medication without asking your doctor. These situations are more common than many people even realize. Medications play an essential role in treating illnesses, controlling chronic conditions, and improving quality of life. However, small mistakes in how medicines are taken ca
Dr Alisha Naaz
Mar 284 min read


GLP-1 Medications: A New Option for People Living with IBD?
Ozempic, Wegovy, Moujaro, Zepbound…these medications have been all over the media as the latest trend in weight loss drugs, but did you know they were developed for another purpose? What are GLP-1 agonists? Glucagon-like peptide 1 (GLP-1) is a naturally occurring human hormone. When a person eats or drinks, the body responds by releasing GLP-1 from the small intestine. This triggers the pancreas to release insulin while suppressing the release of glucagon, slows gastric empty
Sheila Thompson, RN CPHQ
Mar 284 min read


Pharmacogenomics in Oncology
Why the Same Chemotherapy Can Help One Patient and Harm Another? Introduction Chemotherapy remains a cornerstone of cancer treatment across many malignancies, yet patient responses vary dramatically. Two individuals receiving the same regimen can experience entirely different outcomes, ranging from excellent tumour control to severe, life-threatening toxicity. For decades, these differences were largely attributed to age, organ function, or chance. Pharmacogenomics has reveal
Janice Chan
Mar 255 min read
Statins - should their use be supported or shunned?
Introduction Statins have been around for decades, and are one of the most prescribed medicines worldwide. Prescription numbers climb every year, and yet many people still have reservations about taking them. This article explores their use, reputation, and why they are still considered vital in reducing the risk of heart disease. What are statins? Statins are a group of medicines which help reduce levels of “bad” cholesterol, also known as low-density lipoproteins (LDL). C
Georgia McGrath
Mar 183 min read


Wonder Drugs: One Name for Many Maladies
What are these versatile treatments? Recent excitement around GLP-1 medications has brought about interest in health benefits outside of the intended weight control and blood glucose effects. Doctors and researchers have noticed positive effects on other health conditions like chronic kidney disease, even without weight loss. There are quite a few examples of drugs with benefits reaching beyond the initially studied or approved use, and many are still used in an "off-label"
Jackie Lochridge
Mar 112 min read


Antibiotic course and what to consider
Antibiotics Antibiotics are a group medication used to treat or prevent bacterial infections by killing bacteria or stopping them from multiplying. They are prescription drugs that are available as liquids, creams, injections, and pills. Major classes include Beta-lactams (penicillins, cephalosporins), Macrolides, Tetracyclines, Fluoroquinolones, Aminoglycosides, and Glycopeptides. It is important to note that antibiotics treat infections caused by bacteria, such as strep thr
Takudzwa
Mar 52 min read


Revealing Connections: How Gut Microbiome Variability Shapes Drug Response
In clinical medicine, it’s easy to assume that if two patients receive the same diagnosis and the same prescription, their outcomes should look similar. In reality, that’s rarely the case. Some patients respond immediately to treatment, while others see little benefit or experience unexpected side effects. While genetics and lifestyle are often cited as explanations, another factor is gaining attention for its quiet but also very significant role: the gut microbiome. The gut
Marcus M
Mar 23 min read


Aficamten: The Next-Generation Precision Therapy for Hypertrophic Cardiomyopathy
Introduction Hypertrophic cardiomyopathy (HCM) stands as the most common inherited cardiac disease, fundamentally characterized by unexplained thickening of the heart muscle and hypercontractility. In patients with the obstructive subtype (oHCM), the hypertrophied muscle acts like a roadblock, impeding the ejection of blood from the left ventricle into the aorta (Left Ventricular Outflow Tract [LVOT] obstruction). This results in debilitating symptoms such as dyspnea, chest p
Fay
Feb 214 min read


Why Some Common Antibiotics Increase the Risk of Tendon Injuries
For most of us, antibiotics are a quick fix: a small pill that can chase away an infection in a matter of days. But not all antibiotics are created equal. Certain commonly prescribed drugs -- especially a group known as fluoroquinolones -- carry a lesser-known risk: they can damage tendons. From the Achilles to the shoulder, these injuries can appear during treatment or even weeks later, sometimes with sudden, intense pain or long-lasting weakness. Doctors have documented cas
Haneen Awada
Feb 203 min read


Retatrutide: the Future of Obesity Treatment
Introdution Obesity and Type 2 Diabetes Mellitus (T2DM) have evolved into global health crises, contributing to millions of deaths annually and significantly reducing life expectancy. While lifestyle interventions like diet and exercise remain the first line of defense, long-term adherence is notoriously difficult, creating a desperate need for effective pharmacological solutions. Enter Retatrutide: a novel "triple receptor agonist" that is generating massive buzz in the medi
Fay
Feb 193 min read


Datopotamab Deruxtecan: The Next "Magic Bullet" for Triple-Negative Breast Cancer
Introduciton Triple-negative breast cancer (TNBC) represents the subtype of breast cancer with the least favorable outcomes, largely due to its aggressive molecular features and a historic lack of effective targeted treatment options. However, the landscape of oncology is shifting with the rise of Antibody-Drug Conjugates (ADCs). Based on the concept of the "magic bullet" first proposed by Paul Ehrlich, ADCs are designed to selectively deliver cytotoxic chemotherapy directly
Fay
Feb 103 min read


Resmetirom: The First Dawn in the Treatment of MASH
Introduction For decades, the field of hepatology faced a glaring therapeutic void. Metabolically-dysfunction-associated steatohepatitis (MASH), formerly and still widely known as Non-Alcoholic Steatohepatitis (NASH), affects millions globally, driving a rising tide of cirrhosis, liver failure, and hepatocellular carcinoma. Despite its prevalence, affecting an estimated 5.3% of the global adult population, it has earned a reputation as a "graveyard" for pharmaceutical develop
Fay
Feb 43 min read


3 Key Questions to Ask Before Starting a New Medication
You've just had a check-up with your doctor and the decision was made to start you on a new medication. Or maybe you've been discharged from the hospital and have been given a whole LIST of new medications to take. All you want to do is go home. The instructions are on the bottle. You don't need to know anything else...right? WRONG! Your doctor or pharmacist should be telling you all the nitty-gritty details about your new medication. If not, make sure to ask these questions!
Jane Brainard
Feb 44 min read
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