By Kristine Burneko, MSN, APRN, PMHNP-BC, APHN-BC Introduction Psychoneuroimmunology (PNI) is a multidisciplinary field that examines the tridirectional interaction of psychological processes, neurological activity, and immune function. Within clinical practice, PNI provides the mechanistic foundation for mind–body medicine, an evidence-based approach that complements conventional biomedical care by enhancing psychophysiological regulation and response to concurrent treatmen

Chronic pain affects millions worldwide, severely impacting daily life, relationships, and mental health. This debilitating condition can...