Beyond Rogue Cells: How Glioblastoma Recruits an Ecosystem to Survive
Overview: Most people think that cancer is just some cells gone rogue. The truth is more complicated than that. Hanahan introduces the framework that cancer cells themselves do not define cancer biology. Rather, what defines it is the recruitment of other cells to acquire the hallmarks of cancer. The hallmarks of cancer act as the main mechanisms that tumors acquire (1). Glioblastoma Multiforme (GBM) builds overlapping interactions between these mechanisms. GBM is highly aggressive....
